Spatial Moran models, II: cancer initiation in spatially structured tissue
نویسندگان
چکیده
منابع مشابه
Spatial Moran models, II: cancer initiation in spatially structured tissue.
We study the accumulation and spread of advantageous mutations in a spatial stochastic model of cancer initiation on a lattice. The parameters of this general model can be tuned to study a variety of cancer types and genetic progression pathways. This investigation contributes to an understanding of how the selective advantage of cancer cells together with the rates of mutations driving cancer,...
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ژورنال
عنوان ژورنال: Journal of Mathematical Biology
سال: 2015
ISSN: 0303-6812,1432-1416
DOI: 10.1007/s00285-015-0912-1